> sessionInfo()
R version 4.5.1 (2025-06-13 ucrt)
Platform: x86_64-w64-mingw32/x64
Running under: Windows 11 x64 (build 26100)

Matrix products: default
  LAPACK version 3.12.1

locale:
[1] LC_COLLATE=Portuguese_Brazil.utf8  LC_CTYPE=Portuguese_Brazil.utf8    LC_MONETARY=Portuguese_Brazil.utf8 LC_NUMERIC=C                      
[5] LC_TIME=Portuguese_Brazil.utf8    

time zone: America/Sao_Paulo
tzcode source: internal

attached base packages:
[1] grid      stats4    stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] pheatmap_1.0.13             openxlsx_4.2.8.1            org.Mm.eg.db_3.22.0         AnnotationDbi_1.72.0        msigdbr_25.1.1             
 [6] fgsea_1.36.2                apeglm_1.32.0               ggplot2_4.0.1               DESeq2_1.50.2               SummarizedExperiment_1.40.0
[11] Biobase_2.70.0              MatrixGenerics_1.22.0       matrixStats_1.5.0           GenomicRanges_1.62.1        Seqinfo_1.0.0              
[16] IRanges_2.44.0              S4Vectors_0.48.0            BiocGenerics_0.56.0         generics_0.1.4             

loaded via a namespace (and not attached):
 [1] tidyselect_1.2.1    dplyr_1.1.4         farver_2.1.2        blob_1.3.0          Biostrings_2.78.0   S7_0.2.0            fastmap_1.2.0      
 [8] lifecycle_1.0.5     KEGGREST_1.50.0     RSQLite_2.4.5       magrittr_2.0.4      compiler_4.5.1      rlang_1.1.6         tools_4.5.1        
[15] data.table_1.18.0   S4Arrays_1.10.1     bit_4.6.0           curl_7.0.0          DelayedArray_0.36.0 plyr_1.8.9          RColorBrewer_1.1-3 
[22] abind_1.4-8         BiocParallel_1.44.0 babelgene_22.9      withr_3.0.2         numDeriv_2016.8-1.1 scales_1.4.0        MASS_7.3-65        
[29] bbmle_1.0.25.1      cli_3.6.5           mvtnorm_1.3-3       crayon_1.5.3        rstudioapi_0.18.0   httr_1.4.7          bdsmatrix_1.3-7    
[36] DBI_1.2.3           cachem_1.1.0        assertthat_0.2.1    parallel_4.5.1      XVector_0.50.0      vctrs_0.6.5         Matrix_1.7-4       
[43] bit64_4.6.0-1       locfit_1.5-9.12     snow_0.4-4          glue_1.8.0          emdbook_1.3.14      codetools_0.2-20    cowplot_1.2.0      
[50] stringi_1.8.7       gtable_0.3.6        tibble_3.3.0        pillar_1.11.1       R6_2.6.1            lattice_0.22-7      png_0.1-8          
[57] memoise_2.0.1       Rcpp_1.1.0          zip_2.3.3           fastmatch_1.1-8     coda_0.19-4.1       SparseArray_1.10.8  pkgconfig_2.0.3    
>