Intermittent nausea and emesis for more than 20 d. A 58-year-old man, with intermittent nausea and emesis for more than 20 d, was admitted to our gastroenterology department. He complained that abdominal distension could be relieved after vomiting yellow gastric contents. No diarrhea, belching, or fever was found. Two months ago, the patient experienced a LC at a local hospital and postoperative pathology showed chronic calculous cholecystitis. One month after the surgery, his ultrasonography indicated excessive intestinal gas. Other imaging studies like computed tomography (CT) showed no significant difference with the ultrasound findings. The patient lived in Suzhou, China. He did not smoke and was not addicted to alcohol. No relevant family history was reported. On physical examination, a little muscle tension was palpated around the bellybutton and no other positive signs were observed. Increased alkaline phosphatase (ALP) and liver enzymes like alanine transaminase and aspartate aminotransferase were discovered. A fecal occult blood test was positive. A laboratory study regarding the autoimmune liver disease test was done to identify the causes of liver injury and revealed that AMA-M2 was positive. A magnetic resonance imaging (MRI) scan showed a slight dilatation of the intrahepatic bile duct. Abdominal plain films showed much gas in the small intestine. A gastroscopy revealed erosive gastritis and bile reflux gastritis. An abdominal contrast-enhanced CT scan revealed that the gastric cavity and the duodenal lumen were dilated with fluid retention, the proximal jejunal wall thickened with a little exudation surrounding the mesentery, and the adjacent greater omentum thickened with a little effusion. A colonoscopy was added, showing that there was a mucosal eminence lesion in the sigmoid colon (24 cm away from the anus), with a size of 3 cm × 3 cm and erosive surface.