In 2011, a 62-year-old Chinese male with no previous history of brain injury or other neuropsychological diseases and no family history of dementia developed early symptoms of memory decline and cognitive impairment. Five years later, the symptoms had increased to the extent that they affected his daily living. He lost the ability to work as a businessman and to take care of himself. The patient’s MMSE[], Montreal Cognitive Assessment Basic (MoCA-B)[], CDR[], and global deterioration scale scores[] were 1, 0, 2, and 6 points, respectively, indicating that his cognitive function was greatly impaired. The patient’s activities of daily living (ADL) score[] was 65 points, showing that multiple domains of his daily living were affected. Cerebrospinal fluid tau, ptau, and Aβ1-42 levels were all abnormal, which was parallel with a distinctively positive [C-11] Pittsburg compound B positron emission tomography (PET) scan and an [F-18] fluorodeoxyglucose PET scan with a typical AD-like hypometabolic pattern.