A 47-year-old male presented with a gradually increasing, painful soft tissue mass of 7–8 months duration, measuring 4 × 3 cm in the inner side of his right thigh. A computed tomogram (CT) scan revealed an abnormal enhancing lesion in the perianal region. All the visceral organs were found to be normal. No bowel wall thickening, free fluid or abdominal lymphadenopathies were noticed. Subsequently, he underwent a marginal excision for this mass, elsewhere. It was diagnosed as a poorly differentiated carcinoma on biopsy and referred to us in form of a single hematoxylin and eosin (H & E) stained micro section along with a paraffin block for review. At our Hospital, his tumor marker levels for carcino embryogenic antigen (CEA) were normal i.e. 1.8 ng/ml (normal range: 0.3–2.7 ng/ml) On review histology, a diagnosis of a "proximal-type" epithelioid sarcoma was offered. The patient was recommended a wide excision post a magnetic resonance imaging (MRI) for fear of residual disease. However, he was lost to follow-up. Six moths later, he presented with an enlarging mass at the same location. During this time gap, he revealed a history of having undergone adjuvant chemotherapy (CT) and radiotherapy (RT) that were well tolerated. However, he developed difficulty in walking as a result of the persistent lesion. He underwent a chest X-ray along with CT scan and a real time B-mode high frequency ultrasonographic (USG) examination for the persistent mass that was re-excised and re-submitted to us for review. An oval, hypoechoic, solid lesion measuring 2.9 × 2.2 × 2.1 cms was seen in the deep subcutaneous region of the right, upper, inner thigh up to 5–10 mm superior and anterior to the scar of the earlier excision. Other, two, small oval hypoechoic solid lesions of sizes 10 and 8 mm were seen in the subcutaneous layer. The main lesion showed an ill-defined echogenic wall with peripheral echogenic linear echo entering the lesion, suggestive for a lymph node. Eccentric cortical parenchyma showed a distorted architecture. The overlying skin was normal with slightly prominent subcutaneous fat lobules. No significant flow lesion was seen in the color Doppler. Radiologically, the differential diagnoses included a tumor mass vs a lymph node mass.. Grossly, the first excision specimen was in form of grey-white soft tissue bits aggregating to 3.5 × 2 × 2 cms. Details regarding the marginal status were unavailable. On histology, the tumor revealed a multi nodular pattern as a result of investing thin fibrous septa with cells predominantly arranged in a cohesive manner. At places cellular disintegration was observed in combination with hemorrhage resulting in a 'pseudoangiosarcomatous' pattern. The cells were oval to polygonal and exhibited moderate nuclear pleomorphism. Interspersed were larger cells with vesicular nuclei, prominent nucleoli and abundant cytoplasm, including intracytoplasmic inclusions reminiscent of a 'rhabdoid' morphology along with focal areas of tumoral necrosis. Mitoses were noted, however, not conspicuously.. Special histochemical stains were carried out with a wide panel of IHC markers. The reticulin staining highlighted the nodular growth pattern of the tumor.. IHC showed a diffuse strong positivity for CK and vimentin in the tumor cells. CK-7 and EMA were also strongly positive.. Desmin was focally positive. In addition, CD34 was found to be strongly positive. SMA, Myo-D1, CK-20, CEA, S-100, HMB-45, CD 31, C-kit and LCA were negative. A diagnosis of a proximal-type epithelioid sarcoma of was formed. The re-excision showed a similar histology. In addition, increased number of larger cells was noticed along with tumor giant cells and several mitoses.