A 7-month-old female infant from a Sudanese western tribe was referred as a case of malnutrition. At presentation, the patient had confluent eyebrows that appeared arched and well-defined, long curly eyelashes, low front and back hairlines, turned-up nose, down-turned angles of the mouth and thin lips, long philtrum, small lower jaw and protruding upper jaw, microcephaly, excessive body hair, short neck, and small broad hands with simian crease and proximal insertion of the thumb, and clinodactyly of the fifth finger. X-ray showed delayed bone development. She had low-pitched cry, short neck with limited movement, stiff muscle tone (unable to sit, she was still fisting), fixed flexion of both elbows, and she did not show any sign of speaking or babble. Moreover she had tied tongue and thin skin. Her brain stem evoked potential test showed conductive hearing loss. She was about 27 inches in length, her weight was 3 kilograms and there were no records about her birth weight. Her skull circumference was 35 cm. Finally, she showed a number of features not typical of BDLS, including crowded ribs by chest by X-ray (distance between each rib is short). Hepatomegally was shown by ultrasonography. Peripheral blood from the patient was subjected to short-term culture in RPMI 1640 medium for 72 hours. After metaphase arrest through exposure to Colcemide, cells were harvested, treated with hypotonic solution, and then fixed with methanol and acetic acid according to standard procedures. The harvested cells were dropped on clean slides and stained with Wright's stain, for chromosome banding []. The clonality criteria and the karyotypic descriptions were according to the ISCN recommendations []. Analysis of 11 metaphase cells showed 46, XX in all cells.