38-year-old male visited an informal health practitioner with complaints of burning micturition and abdominal pain. He received injection of Diclofenac in his left cubital fossa. Following this, the patient developed excruciating pain that was sudden in onset and radiating along the borders of the left forearm. He was referred to a nearby hospital, where the Duplex ultrasonography (DUS) was done that did not show any abnormality in the symptomatic arm. The patient was referred to our hospital as the symptoms progressed and were refractory. The patient arrived at our hospital about 15 hours following injection and presented with complaints of bluish discolouration of left hand, reduced movement in left wrist and fingers, pain in left forearm that increased with digital movements. On examination, the left hand appeared discoloured with delayed capillary filling time. There was reduced temperature in the symptomatic limb when compared to the contralateral limb. The patient maintained flexion of the wrist joint. Brachial, ulnar and radial pulses were palpable. Passive extension was extremely painful to the patient. Saturation of the limb was not recordable in the ipsilateral limb.