A 25-year-old female presented with severe headache and was diagnosed with migraine. She was started on TPM 25 mg/day; however, she stopped the treatment after 3 days without consultation as her headache was not relieved. After 5 days of stopping the treatment with TPM, she presented at the emergency clinic of a hospital with complaints of blurred vision and severe pain in both the eyes, which were of a few hours in duration. She also complained of colored halos and headache associated with nausea with no family history of eye-related disorders. On ophthalmic examination, the visual acuity was found to be 3/60 in both the eyes, and did not show improvement in visual acuity in the pinhole test. There was bilateral lid edema, ciliary congestion, and chemosis. Both anterior chambers were found to be shallow, appeared occluded in the periphery, and pupils were reactive. Applanation tonometry revealed high intraocular pressure (IOP) of 34 and 32 mmHg, in the right and left eyes, respectively. A diagnosis of AACG, precipitated following oral administration of TPM, was made. While, laser peripheral iridotomy would have been an ideal procedure for AACG, due to presence of choroidal effusion along with anterior migration of anterior structures this treatment option was not considered in this case. She was hence started on acetazolamide tablets 250 mg four times a day (QID), pilocarpine 2% eye drops QID, travoprost 0.004% OD, and dorzolamide 2% eye drops three times a day (TID). Since she had already stopped TPM, she was advised not to take it again and was reviewed the next day. The repeat ophthalmic examination on the second day showed improved vision (6/60) in both the eyes, reduction in conjuctival chemosis, and improved depth of anterior chamber, while it continued to be shallow peripherally. IOP measurements were repeated using applanation tonometry and were found to be 20 and 18 mmHg, in the right and left eyes, respectively. On the third day, her vision improved to 6/12 in the right eye and 6/6 partial (p) in the left with IOP 10 and 14 mmHg, respectively. The ophthalmoscopic examination of disc and macula was normal in both the eyes. Subsequent examination on the fifth day showed improved visual acuity 6/6 p in both the eyes and IOP was 14 and 12 mmHg and the anterior chamber appeared well formed. She was advised to taper the anti-glaucoma medication and was examined a month later when her visual acuity was 6/6, with IOP 14 mmHg in both the eyes and was then advised via evaluation by a glaucoma specialist. All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008. Written informed consent was obtained from the patient for which identifying information is included in this case report.