A 37-year-old female patient experienced intermittent hematuria with dysuria for 10 days, with dark red vegetation prolapsed from the urethra during urination. The patient had no evident urinary urgency, pyuria, waist discomfort, or fever. During the physical examination, a dark red strip-shaped mass protruded from the urethral orifice. This mass was soft, and its root could not be explored. Ultrasound showed a 36 mm × 17 mm mild hydronephrosis in the right kidney, and other echoes were observed at the opening of the bladder in the lower part of the right ureter. The inner diameter of the lower end of the right ureter was 8 mm, and the inner diameter of the upper segment was 6 mm. Computed tomography urography (CTU) examination showed a strip filling defect at the entrance of the bladder on the right ureter. The filling of the bladder was satisfactory, and a nodular filling defect was observed on the posterior wall. Afterwards, the patient received ureteroscopy diagnosis under general anesthesia. During operation, the exposed mass was held with tissue forceps, and the tension was slightly maintained. A ureteroscope was used to examine the bladder through the urethra, and the mass was seen protruding from the right ureteral opening. The silk and ureteroscope were utilized to assess the right ureter, and the base of the mass was found in the middle and lower section of the right ureter. The mass was strip-shaped, the surface was smooth, and no obvious hemorrhage and necrosis were observed. The basal mucosa of the mass showed edema, and the tumor tissue did not completely block the ureteral cavity. Then, under the direct view of the ureteroscope, a 200 mm Ho:YAG laser fiber with an energy setting of 1 J and a frequency of 15 Hz was used to remove the tumor by cutting off along the its base. The tissue was clamped out of the tumor, and the right ureter was placed with an F5 double J tube. The long grape-shaped mass was 12 cm in length with a smooth surface. The diameter of the tube was approximately 0.8–1.8 cm, and the edema was translucent. Combined with hematoxylin and eosin staining and immunohistochemical nucleus Gata3 (+), CK20 (−) in the cytoplasm was diagnosed as a polyp formed by ureteric epithelial proliferation. The double J tube was removed 3 months after the operation by ureteroscopy which was performed to review the wound. The patient received the urinary system B-ultrasound 6 months after the operation, indicating no ureteral stenosis or hydronephrosis.