A 63-year-old male patient with an Eastern Cooperative Oncology Group index of 1 was referred to our hospital for a single, large liver metastasis, twelve months after a radical total gastrectomy and DII lymphadenectomy for upper third gastric adenocarcinoma. The initial pathology report identified a pT3N1M0LV1, moderate-differentiated, gastric adenocarcinoma. As an adjuvant treatment, the patient received 12 cycles of FOLFOX chemotherapy. During the present admission, the abdominal computed tomography (CT) revealed a unique liver metastasis located in the segments 5 and 6, of 105/85 mm in diameter. The 18-FDG PET-CT scan revealed no extrahepatic disease. Surgical resection by an open approach of liver metastasis was decided. The peritoneal washing revealed no malignant cytology, and intraoperative ultrasonography showed no additional liver metastatic disease. We performed a non-anatomical liver resection, without inflow control due to significant peritoneal adhesions in the liver hilum, secondary to previous lymphadenectomy. The patient was discharged after seven days, with an uneventful recovery. The pathology report confirmed metastatic disease with a gastric origin. Six months after the second surgical procedure, the patient developed a local liver recurrence, of 84/73 mm diameter. The thoracic, abdominal, and pelvic CT revealed no extrahepatic metastases. The surgical resection of the liver recurrence was performed, with no postoperative morbidities, and the patient was discharged after eight days. Three months after the latest surgery, the patient is under adjuvant chemotherapy, with no imagistic signs of additional recurrences.