The patient, an 11-year-old female, presented for a homeopathic consultation on February 22, 2018. The patient had one-sided headaches preceded by an aura, with a transitory loss of vision in the form of central scotoma or contralateral hemianopia. The vision was dim or foggy at times. Later episodes were followed by formication of the left hand and vomiting, without ameliorative effect. About 10 episodes of headache were seen in 6 months, where the patient used analgesics like paracetamol or ibuprofen. Headaches lingered for 2 days after conventional therapy. The patient had two episodes of head injury, at 1.5 years and 6 years of age, with a concussion during the second incident, where the response time was delayed for 3 h. She had atopic dermatitis during her early childhood, Mycoplasma pneumoniae infection at 3 years of age, recurrent herpetic eruptions on the nasal mucosa at the age of 9 years, and recurrent aphthae since the age of 10 years. She is also allergic to fur and pollen. The patient was regularly attended to, by conventional medicine specialists. The child’s parent and maternal grandmother had a positive medical history of migraine. Magnetic resonance imaging at the beginning of consultation revealed a septate PC measuring 9.0 mm (shown in ). The MR angiography, hematological tests, thyroid hormone assay, and serology for B. burgdorferi were normal. No specific ECG or ophthalmologic or endocrine pathology was found. Infections, meningitis, malignant tumor growth, hypertensive encephalopathy, antiphospholipid syndrome, and stroke were not confirmed. Migraine with aura – ICD: G43.1; congenital cerebral cyst – ICD: Q04.6 []. On February 22, 2018, the patient presented with recurrent headaches. On further examination, it was found that the migraine affected the patient’s concentration and performance to an extent that it made day-to-day activities difficult, and she could not attend school during those days. The headache aggravated with exertion and on fasting. She was sensitive to cold weather and had difficulty in falling asleep; she complained of formication in the extremities and perspiration over the back and face. On inquiring about her nature, the mother described the child as being compassionate. She used to cling to the parents when younger and did not like staying alone. The child was excessively worried about the health of her loved ones and would have nightmares often. Classical homeopathy provides holistic treatment tailored to the patient based on the symptomatology presented. The emotional state where she wanted the company of her mother and would cling on to her, coupled with her sympathetic nature, anxiety, and physical symptoms like her desire for ice cream, pointed toward the homeopathic remedy Phosphorous. Other remedies such as Stramonium and Causticum also show symptoms such as strong clinging to the mother and sympathetic behavior respectively; however, in Stramonium, the clingy nature is seen due to fear with severe aggressive and violent behavior, while in Causticum, neurological affections are seen with sympathetic behavior toward social suffering rather than physical [] (online suppl. Fig. S1; for all online suppl. material, see ). Prescription: February 22, 2018; Phosphorous 200 CH, one dose. Follow-up of the patient is shown in. The patient was treated homeopathically for a period of 5 years, with 9 follow-ups during this time. During this period, 2 remedies were prescribed; Phosphorous in different potencies initially, under which she improved consistently. After 9 months of initial prescription, she received a repetition of Phosphorous 200 CH as there was a relapse of migraines from antidoting effect, from suppression of aphthous ulcers with topical application. After this, the homeopathic physician perceived that with certain triggers, the migraine relapsed. This meant that the case was not stabilizing with 200 CH. Therefore, a repeated dosing was opted for, with LM potency. It is a practice to give consecutively higher potencies with the LM scale in homeopathy whenever a need for more stimulation is observed, for example, when the improvement regresses or hits a plateau. Three years and 4 months into the treatment, the repeat magnetic resonance imaging showed normal brain study, remarking the resolution of PC (). However, milder episodes of migraine continued and so did the treatment. It should be noted that around the same time, the patient expressed her old, suppressed herpes simplex eruptions. This is considered a good change in homeopathy. The effort with homeopathy is always to revert the immune status of the organism to how it was before developing the diseases being addressed. During this, it can happen that old conditions that were suppressed with the aid of superficial treatments make an appearance again. This is a welcome change, and the new situation must be assessed anew for homeopathic treatment. If they do not resolve on their own, they will need a remedy, as happened in this case. Natrum muriaticum 200 CH was prescribed when the herpes persisted and became the main issue. The herpes resolved with Natrum mur, and the patient was generally well. The mother of the patient has provided her experience with homeopathic treatment for her daughter’s condition. Though migraine relapsed a few times with external triggers, the PC did not return (), and the episodes were milder when compared to before homeopathic therapy, with improved quality of life (shown in ).