TCR = False
-TCR_LOW = False
-TCR_HIGH = True
-CD28 = True
-TGFBETA = False
-IL2 = False
-IL2R = False
-AP1 = False
-FOS = False
-FOS_D =False
-FOS_DD = False
-FOS_DDD = False
-JUN = False
-ERK = False
-MEK2 = False
MEK1 = False
-TAK1 = False
-MKK7 = False
-JNK = False
-RAF = False
-RAS = False
-CA = False
-NFAT = False
-PKCTHETA = False
-NFKAPPAB = False
-PI3K_LOW = False
-PI3K_HIGH = False
-PI3K = False
-PIP3_LOW = False
-PIP3_HIGH = False
-PIP3 = False
-PTEN = True
-PDK1 = False
-AKT = False
-MTORC1 = False
-MTORC2 = False
-MTOR = False
-MTORC1_D = False
-MTORC2_D = False
-MTORC2_DD = False
-MTOR_D = False
-MTOR_DD = False
-MTOR_DDD = False
-MTOR_DDDD = False
-RHEB = False
-TSC = True
-S6K1 = False
-PS6 = False
-SMAD3 = False
-JAK3 = False
-STAT5 = False
-STAT5_D = False
-STAT5_DD = False
-STAT5_DDD = False
-FOXP3 = False
-CD25 = False
-CD122 = True
-CD132 = True
-IL2_EX = False
FOXO1 = True
FOXO1_P = False
FOXO1_P_D = False
FOXO1_P_DD = False
FOXO1_P_DDD = False
CK2 = False
AKT_OFF = False
MTORC1_OFF = False
NFAT_OFF = False
IL2RA = False
IL2RA_D = False

-1: TCR* = TCR_LOW or TCR_HIGH
1: CK2* = TCR_HIGH
-1: RAS* = (TCR and CD28) or (RAS and IL2_EX and IL2R)
-1: RAF* = RAS
-1: MEK2* = RAF
1: MEK1* = RAF
-1: ERK* = MEK2
-1: FOS* = ERK
-1: PKCTHETA* = TCR_HIGH or (TCR_LOW and CD28 and MTORC2)
-1: TAK1* = PKCTHETA
-1: MKK7* = TAK1
-1: JNK* = MKK7
-1: JUN* = JNK
-1: FOS_D* = FOS
-1: FOS_DD* = FOS_D
-1: AP1* = FOS and JUN
-1: CA* = TCR
-1: NFKAPPAB* = PKCTHETA or AKT
-1: NFAT* = CA and not NFAT_OFF
-1: IL2* = ((AP1 and NFAT and NFKAPPAB) or IL2) and not FOXP3
-1: IL2R* = CD25 and CD122 and CD132
1: IL2RA* = IL2 and IL2R
1: IL2RA_D* = IL2RA
-1: PI3K_LOW* = (TCR_LOW and CD28) or (PI3K_LOW and IL2RA_D)
-1: PI3K_HIGH* = (TCR_HIGH and CD28) or (PI3K_HIGH and IL2RA_D)
-1: PI3K* = PI3K_LOW or PI3K_HIGH
-1: PIP3_HIGH* = PI3K_HIGH and not PTEN
-1: PIP3_LOW* = PI3K_LOW and not PTEN
-1: PIP3* = PIP3_LOW or PIP3_HIGH
-1: PDK1* = PIP3
-1: AKT* = (PDK1 and MTORC2) and not AKT_OFF
-1: TSC* = not AKT
-1: RHEB* = not TSC
-1: MTORC1* = RHEB and not MTORC1_OFF
-1: MTORC2* = PI3K_HIGH or (PI3K_LOW and not S6K1)
-1: MTORC1_D* = MTORC1 
-1: MTORC2_D* = MTORC2
-1: MTOR* = MTORC1_D and MTORC2_D
-1: MTOR_D* = MTOR
-1: MTOR_DD* = MTOR_D
1: MTOR_DDD* = MTOR_DD
-1: S6K1* = MTORC1
-1: PS6* = S6K1
-1: SMAD3* = TGFBETA
-1: JAK3* = IL2R and IL2_EX
-1: STAT5* = JAK3
-1: STAT5_D* = STAT5
-1: FOXP3* = (not MTOR_DD and (STAT5 or (NFAT and AP1 and STAT5 and FOXO1))) or (NFAT and SMAD3)
-1: CD25* = FOXP3 or (AP1 and NFAT and NFKAPPAB) or STAT5
-1: PTEN* = (FOXO1 and MEK1) and not CK2
1: FOXO1* = not AKT
-1: IL2_EX* = IL2 or IL2_EX