The patient is a 38-year-old male who came to the Oral and Maxillofacial Surgery Department of the Hospital Universitari Vall d'Hebron, referred from another centre, due to a mandibular tumour that had been present for 1 year.

His pathological history included being a former injecting drug addict, HCV positive and HIV positive on antiretroviral treatment. On examination, there was a right mandibular tumour approximately 5 cm in size, fixed and hard in consistency, and the oral mucosa remained intact. The orthopantomography showed a mixed lesion with calcifications in its interior affecting the right hemimandible.

The CT scan showed an expansive mixed lesion in the body of the right mandible that destroyed the cortices measuring 4.5x3x3.3 cm.

The biopsy performed showed a calcifying epithelial odontogenic tumour.
The patient underwent a right hemimandibulectomy with microsurgical reconstruction with fibula.

Pathological anatomy revealed a mass measuring 4 x 2.5 cm with an irregular surface, heterogeneous appearance, congestive areas and remnants of teeth, which confirmed the diagnosis of calcifying epithelial odontogenic tumour of the mandible infiltrating periosteal soft tissues. The mentonian nerve showed no invasion and the intraoperative biopsy of the left facial chain lymph node showed no metastasis.

Postoperative evolution was favourable and he was discharged on a tolerated diet and with wound control in outpatient clinics.

