51-year-old male. Unrelated aetiology ACKD, hypertensive and on haemodialysis since 2005, with first kidney transplant immediately failed due to non-immunological arterial thrombosis in October 2007, receiving a transfusion of 2 red blood cell units on admission. Sporadic increase in transaminases in 2009, becoming persistent since December 2010 (maximum figure 28/40 IU/l GOT/GPT). Occult HCV was diagnosed as 14,700 copies/µg total RNA in CMSP (RNA in serum by ultracentrifugation and high-sensitivity anti-HCV core antibody, negative). Normal ultrasound and FibroScan®. There was no external possibility of contagion, and PCR and viral serology was performed on the rest of the patients in the unit, as well as on the healthcare staff, without detecting new cases of classic HCV infection. She received a second kidney transplant in October 2013, and was treated with thymoglobulin (TG), tacrolimus (FK), mycophenolate (MMF) and corticosteroids. Seventeen months after the transplant, the viral load in PBSC is undetectable, and the serum ultracentrifugation RNA and the highly sensitive anti-HCV core antibody remain negative.

