A 60-year-old man with a history of arterial hypertension, aortic and mitral valve disease, left parietal haematoma, left inguinal and umbilical herniorrhaphy, diagnosed 3 years ago with stage A/O chronic lymphocytic leukaemia and under follow-up by the haematology department of our hospital, without treatment. A control thoracoabdominal-pelvic CT scan showed lymphadenopathies in the cervical, axillary, mediastinal, retroperitoneal and inguinal areas, as well as a 3 cm hypodense image of the left prostate lobe, with a poor plane of separation from the left levator ani muscle. The patient had no urological symptoms.
Rectal examination revealed a poorly defined prostate at both bases, with a diffuse increase in consistency in both lobes. PSA was 0.9 ng/ml. Transrectal ultrasound shows a prostate measuring 28.5 x 43.4 x 50.8 mm and 32.9 ml, with heterogeneous parenchyma and several hyperechoic areas at both bases. The right vesiculoprostatic angle is effaced. Prostatic biopsies were taken by sextants.
The pathology report describes a prostatic parenchyma with a dense cellular infiltrate consisting of small lymphocytes suggestive of infiltration by chronic lymphocytic leukaemia.

