Attention: This is an archive version of the HELP CDSS for documentation purposes. It is neither updated nor actively maintained!
Therapy
T1. Antibiotic Therapy
T1.4. Therapy duration
T1.4.2. Oral Sequence Therapy
T1.4.2.2. Oral sequence therapy with Levofloxacin
Dosage Levofloxacin p. o.
GFR >50 1-2 x 500 mg
GFR 30-50 1-2 x 250 mg
GFR <30 1-2 x 0.125 mg
CHD 1 x 0.125 mg
CVVH 1-2 x 500 mg

CAVE
High risk for adverse events including QT time extension, tendinitis, neurotoxicity
Adjustment to kidney function required
Abbreviations:
CHD Chronic hemodialysis
CVVH Continuous venovenous hemofiltration
GFR Glomerular filtration rate