Attention: This is an archive version of the HELP CDSS for documentation purposes. It is neither updated nor actively maintained!
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Unclear relevance of blood cultures, persistent clinical indication of infection or risk factors (e.g. implanted foreign material)?
Take
two pairs
of blood cultures again.
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Is a central catheter present?
Collect one of the blood culture pairs
centrally
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Permanent
intravascular foreign bodies
present?
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Note:
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Is the
follow-up blood culture positive
?
If "No"
No antibiotic therapy necessary (if necessary, terminate).
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CAVE:
| Negative blood cultures which were taken under already ongoing effective antibiotic therapy have a severely limited significance . |
Explanatory Notes:
| For the identification of a relevant bacteremia, ≥2 pairs of blood cultures (follow-up blood cultures) should be taken again. | |
| If the patient has permanent intravascular foreign bodies (e.g. heart valve replacement, pacemaker/ICD, large vessel stents), targeted antibiotic therapy can be considered until the final results of these blood cultures are available . | |
| In case of negative blood cultures an antibiotic therapy is not necessary (or can, if it was started, usually be stopped again). |