Izzie Stevens
Grey's Anatomycharacter
Dr. Isobel Stevens.jpg
The Season 6 promotional photo of Katherine Heigl as Dr. Izzie Stevens
First appearance"A Hard Day's Night" (1.01)
March 27, 2005
Last appearance"I Like You So Much Better When You're Naked" (6.12)
January 21, 2010
(as series regular)
"Leave a Light On" (16.16)
March 5, 2020
(stand-in)
Created byShonda Rhimes
Portrayed byKatherine Heigl
Season(s)1 – 6; 16 (stand-in)
In-universe information
Full nameIsobel Katherine Stevens
TitleM.D.
OccupationSurgical intern
(seasons 1–3)
Surgical resident (seasons 4–6)
Attending surgical oncologist (season 16)
FamilyRobbie Stevens (mother)
Unnamed deceased maternal grandmother
Spouse
Alex Karev
(m. 2009;div. 2010)
(reconciled)
SignificantotherHank (ex-boyfriend)
Denny Duquette
(fiancé)
George O'Malley
ChildrenAlexis and Eli (twins; with Alex)
Hannah Klein (biological daughter, placed for adoption aged 16)
ReligionCatholicism